Startups
SynAct Pharma
Edit

SynAct Pharma

http://www.synactpharma.com/
Last activity: 16.04.2025
Active
Categories: BioTechDevelopmentITResearch
SynAct Pharma is a biotech company aiming at resolving inflammation by leveraging melanocortin biology. Our lead asset AP1189 is in phase 2 development for the treatment of rheumatoid arthritis. AP1189 is an immunomodulatory small molecule delivered as a once-daily tablet. The mode of action is selective melanocortin receptor type 1 and 3 agonism, making it first-in-class. Activation of these receptors results in reduced secretion of proinflammatory cytokines by neutrophils and in conversion of macrophages towards clearing away cellular debris in hyper-inflamed tissue – two effects that together induce resolution of inflammation. The Phase 2a BEGIN study in patients with rheumatoid arthritis reported very promising efficacy and safety results in November 2021 - next step is to open an IND with FDA to get advice on further development. Due to the known Mode of Action, then AP1189 was also tested in COVID-19 positive patients with respiratory insufficiency. Results were reported in July 2021, demonstrating 4 days earlier respiratory recovery, 3 days earlier hospital discharge and more than 50% reduced risk of progressing to needing mechanical ventilation.
Followers
971
Website visits
24.1K /mo.
Mentions
47

Overview

Location
Sweden, Scania, Lund
Employees
1-10
Founded date
2013

Mentions in press and media 47

DateTitleDescription
Sign up to seeSign up to seeSign up to see
Apr 16, 2025A New Dawn in Clinical Trials: Innovations in Immunotherapy and Dengue TreatmentThe world of medicine is a battlefield. Every day, researchers and companies fight against diseases that plague humanity. Two recent developments shine a light on this ongoing struggle: SynAct Pharma’s resomelagon for dengue and Elicera The...
Apr 14, 2025BioStock: SynAct Pharma’s resomelagon under clinical evaluation for dengueBioStock: SynAct Pharma’s resomelagon under clinical evaluation for dengue Mon, Apr 14, 2025 10:44 CET Report this content An investigator-initiated phase II study has been launched with SynAct Pharma’s lead candidate, resomelagon, in patie...
Mar 6, 2025BioStock: SynAct Pharma secures key US patentBioStock: SynAct Pharma secures key US patent Thu, Mar 06, 2025 09:19 CET Report this content SynAct Pharma has been granted a pivotal US patent protecting the crystal form of resomelagon, a drug candidate currently in phase IIb clinical de...
Feb 19, 2025BioStock: SynAct Pharma advances trial with boosted fundingBioStock: SynAct Pharma advances trial with boosted funding Wed, Feb 19, 2025 11:45 CET Report this content In the fourth quarter, SynAct Pharma focused on progressing its Phase IIb study, ADVANCE, evaluating resomelagon in newly diagnosed ...
Nov 25, 2024Ascentage Pharma Appoints Ms. Marina S. Bozilenko and Dr. Debra Yu as Independent Non-Executive DirectorsROCKVILLE, Md. and SUZHOU, China, Nov. 25, 2024 /PRNewswire/ -- Ascentage Pharma (6855.HK), a global biopharmaceutical company engaged in discovering, developing and commercializing therapies to address global unmet medical needs primarily ...
Apr 2, 2024BioStock: Synact focuses on pushing forward rheumatoid arthritis projectBioStock: Synact focuses on pushing forward rheumatoid arthritis project Tue, Apr 02, 2024 10:41 CET Report this content SynAct Pharma is intent on making a turnaround after posting disappointing study results with lead asset resomelagon. T...
Dec 19, 2023Revolutionizing Inflammatory Disease Treatment: A New Era in Biotech Healthcare?Today we explore the work of SynAct Pharma, an innovative biotech and healthcare startup from Lund, Sweden. Focused on the development of drugs for acute deterioration in inflammatory diseases, SynAct Pharma deploys groundbreaking approache...
May 29, 2023Find your next investment at the BioStock Life Science Spring Summit on May 30 and 31!Find your next investment at the BioStock Life Science Spring Summit on May 30 and 31! Mon, May 29, 2023 09:45 CET Report this content It is finally time for BioStock Life Science Spring Summit 2023! Around 30 companies from a wide range of...
Jul 8, 2022SynAct Pharma AB publishes prospectus for list change to Nasdaq StockholmSynAct Pharma AB publishes prospectus for list change to Nasdaq Stockholm Fri, Jul 08, 2022 09:45 CET Report this content SynAct Pharma AB (“SynAct” or the “Company”) announced on June 28, 2022 that Nasdaq Stockholm’s listing committee has ...
Show more

Reviews 0

Sign up to leave a review

Sign up Log In

FAQ about SynAct Pharma

When was SynAct Pharma founded?

SynAct Pharma was founded in 2013.

What has the press written about SynAct Pharma?

Parsers VC has collected 47 articles mentioning SynAct Pharma, among them “A New Dawn in Clinical Trials: Innovations in Immunotherapy and Dengue Treatment” (Apr 16, 2025) and “BioStock: SynAct Pharma’s resomelagon under clinical evaluation for dengue” (Apr 14, 2025).

Is SynAct Pharma still active?

Yes, SynAct Pharma is active; its latest activity on Parsers VC dates from Apr 16, 2025.