Surface Oncology is a clinical-stage immuno-oncology company focused on using its specialized knowledge of the biological pathways critical to the immunosuppressive tumor microenvironment (TME) for the development of next-generation therapies to help patients suffering with cancer. Recent advances in understanding how the immune system fights cancer has created a first wave of immunotherapies with profound benefits for some patients. These first-generation therapies, or "checkpoint inhibitors", have been groundbreaking, but only a relatively small subset of patients is deriving long-term benefit. We believe that the lack of a broad and sustained clinical response is because these first-generation therapies only target one component of the immunosuppressive TME and a broader, more multi-faceted therapeutic approach is required.
We are a team on a mission to deliver transformative outcomes for people with cancer by breaking through the frontiers of immuno-oncology research. Our diverse clinical and preclinical pipeline of immune-enhancing antibody candidates target the innate and adaptive arms of the immune system to deliver dramatically different therapies for patients and their families.
Surface is leveraging its deep understanding of TME biology to target factors and cells that suppress patients’ anti-tumor immune response. Our broad attack on the TME has the potential to convert patients’ non-responsive ‘cold’ tumors into immune-active ones. We push ourselves to break through across all dimensions of our work.
From a discovery perspective, Surface leverages its world-class SAB to identify new targets and takes an aggressive approach towards generating diverse, highly-specific antibodies, which allows our scientists to thoroughly explore the relevant biology. Our antibody discovery approach generates therapeutic-quality antibodies, as well as unique tools to explore the biology of the tumor microenvironment.
Location: United States, Massachusetts, Cambridge
Employees: 51-200
Total raised: $35M
Founded date: 2014
Investors 4
Date | Name | Website |
- | K2 HealthV... | k2healthve... |
- | F-Prime Ca... | fprimecapi... |
- | Atlas Vent... | atlasventu... |
- | Eight Road... | eightroads... |
Funding Rounds 1
Date | Series | Amount | Investors |
08.01.2015 | Series A | $35M | - |
Mentions in press and media 7
Date | Title | Description | Source |
20.03.2024 | Startup Lands $150M for Delicate Dance Between Cancer Cells ... | Cancer immunotherapy comes in several forms, and one area of growing research interest is a type of ... | medcitynew... |
11.08.2020 | SURFACE ONCOLOGY, INC. Surface Oncology Reports Financial R... | CAMBRIDGE, Mass., Aug. 11, 2020 (GLOBE NEWSWIRE) -- Surface Oncology (Nasdaq: SURF), a clinical-stag... | marketscre... |
23.04.2018 | Surface Oncology Closes $119.5 Million Financing | CAMBRIDGE, Mass., April 23, 2018 (GLOBE NEWSWIRE) -- Surface Oncology, Inc., an immuno-oncology comp... | citybizlis... |
09.04.2018 | Term Sheet — Monday, April 9 | BIG PLAYS Good morning, Term Sheet readers. Paid Content What you need to know about growing cyberat... | fortune.co... |
08.11.2016 | Stanford team preps first human CRISPR study for sickle c... | Matthew Porteus Stanford scientists say they have been able to use CRISPR gene editing tech to ... | endpts.com... |
08.01.2015 | Surface Oncology Raises $35M to Develop Cancer Immunotherapi... | Share Share on Facebook Share on Twitter LinkedIn Email Reprints Surface Oncology of Cambridge, MA, ... | xconomy.co... |
08.01.2015 | Surface Oncology Closes $35M Series A Funding Round | Surface Oncology, a Cambridge, Mass.-based company developing cancer immunotherapies, closed a $35m ... | finsmes.co... |