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| Sep 12, 2024 | The Hidden Struggles of X-Linked Hypophosphatemia: A Call for Awareness and Action | X-linked hypophosphatemia (XLH) is a name that may not ring a bell for many. Yet, for those affected, it’s a daily battle. A recent analysis from the XLH Disease Monitoring Program (DMP) sheds light on the harsh realities faced by adults li... |
| Sep 9, 2024 | More space for healthtech start-ups on the Novartis Campus |
Digitalisation is one of the megatrends in the healthcare sector. It not only promises greater efficiency, but also new possibilities in diagnostics and therapeutics. As this field requires expertise that traditional healthcare companies o... |
| Oct 18, 2022 | SOTIO to Present the AURELIO-04 Phase 2 Study Design and Findings from BOXR Research at the SITC Annual Meeting | BASEL, Switzerland and CAMBRIDGE, Mass., Oct. 18, 2022 (GLOBE NEWSWIRE) -- SOTIO Biotech, a clinical stage immuno-oncology company owned by PPF Group, announced today that it will share two poster presentations, namely the Phase 2 AURELIO-0... |
| Sep 14, 2022 | SOTIO Bolsters Leadership Team with Appointment of Martin Steegmaier as Chief Scientific Officer | PRAGUE, Czech Republic, Sept. 14, 2022 (GLOBE NEWSWIRE) -- SOTIO Biotech, a clinical stage immuno-oncology company owned by PPF Group, announced the appointment of Martin Steegmaier, Ph.D., MBA, as chief scientific officer. Martin Steegmaie... |
| Sep 12, 2022 | SOTIO Strengthens Management Team with Appointment of Robyn Hunter as Chief Financial Officer | CAMBRIDGE, Mass., Sept. 12, 2022 (GLOBE NEWSWIRE) -- SOTIO Biotech, a clinical stage immuno-oncology company owned by PPF Group, announces the appointment of Robyn Hunter as chief financial officer. Ms. Hunter is an accomplished CFO who bri... |
| Jul 26, 2022 | SOTIO Doses First Patient in AURELIO-04 Phase 2 Trial of SOT101 in Combination with KEYTRUDA® (pembrolizumab) | AURELIO-04 will enroll up to 320 patients and test the combination in multiple solid tumor indications
Clinical collaborator, MSD (Merck & Co., Inc., Rahway, NJ, USA), will supply KEYTRUDA for the study that is being conducted in Europe... |
| Apr 27, 2022 | Oral Presentation of Interim Data from the AURELIO-03 Study of SOT101 at the 2022 ASCO Annual Meeting | SOTIO will share interim safety and efficacy results from SOTIO’s AURELIO-03 study on Saturday, June 4
AURELIO-03 is a Phase 1/1b dose escalation study of the interleukin-15 superagonist SOT101 as monotherapy and in combination with pembrol... |
| Apr 26, 2022 | SOTIO Initiates CLAUDIO-01 Trial with Antibody-Drug Conjugate SOT102 in Patients with Gastric and Pancreatic Cancer | CLAUDIO-01 is the first-in-human trial of SOT102, a CLDN18.2 (Claudin 18.2) targeting antibody-drug conjugate (ADC)
The trial will enroll up to 109 patients with gastric and pancreatic cancer
PRAGUE, Czech Republic, April 26, 2022 (GLOBE NE... |
| Apr 12, 2022 | Interim Data from the Phase 1/1b AURELIO-03 Trial of SOT101 Presented at the AACR 2022 Annual Meeting | PRAGUE, Czech Republic and BASEL, Switzerland and CAMBRIDGE, Mass, April 12, 2022 (GLOBE NEWSWIRE) --
Interim Results of the Phase 1 AURELIO-03 study of SOT101 in combination with pembrolizumab for patients with advanced metastatic tumors w... |
| Mar 16, 2022 | SOTIO Announces Oral and Multiple Poster Presentations on Key Clinical Programs at the American Association of Cancer Research Annual Meeting (AACR) 2022 | Oral presentation will focus on interim efficacy and safety data from the Phase 1/1b AURELIO-03 study of SOT101 in combination with pembrolizumab
Poster presentations will feature preclinical data on SOTIO’s immunocytokine SOT201 and the BO... |
| Dec 8, 2021 | SOTIO Announces Clinical Collaboration with MSD to Evaluate IL-15 Superagonist, SOT101, in Combination with KEYTRUDA® (pembrolizumab) in Patients with Solid Tumors | The Phase 2 AURELIO-04 study is expected to enroll up to 300 patients across six different indications
The study will be conducted in the US and selected European countries and will begin in the first half of 2022
PRAGUE, Czech Republic, De... |
| Dec 8, 2021 | SOTIO Announces Clinical Collaboration with MSD to Evaluate IL-15 Superagonist, SOT101, in Combination with KEYTRUDA® (pembrolizumab) in Patients with Solid Tumors | The Phase 2 AURELIO-04 study is expected to enroll up to 300 patients across six different indications
The study will be conducted in the US and selected European countries and will begin in the first half of 2022
PRAGUE, Czech Republic, De... |
| Dec 3, 2021 | Little European biotech Sotio nabs a super $316M funding round for its superagonist work | In one of the biggest funding rounds for a European biotech ever, Czech Republic cancer company Sotio Biotech has grabbed a huge 280 million euro ($316 million) raise.
The immuno-oncology company, owned by the PPF Group, will use the cash t... |
| Dec 3, 2021 | Thank you | This is the web version of Term Sheet, a daily newsletter on the biggest deals and dealmakers. Sign up to get it delivered free to your inbox.
My fantastic Term Sheet readers: That’s right—today is my last day at Fortune, making this my las... |
| Dec 3, 2021 | Thank you | This is the web version of Term Sheet, a daily newsletter on the biggest deals and dealmakers. Sign up to get it delivered free to your inbox.
My fantastic Term Sheet readers: That’s right—today is my last day at Fortune, making this my las... |
| Dec 2, 2021 | SOTIO Secures 280m of Funding to Expand and Advance Clinical Pipeline | PPF Group provides funding to advance SOTIO through key clinical milestones
Proceeds shall be used to conduct two phase 2 studies with SOT101, including a checkpoint inhibitor combination trial Three programs (SOT102, BOXR1030, and SOT201) ... |
| Dec 2, 2021 | Sotio Biotech Raises €280M in Funding | Sotio Biotech, a Prague, Czech Republic-based clinical stage immuno-oncology company, secured €280m in funding.
PPF Group made the investment.
Led by Radek Spisek, Ph.D., CEO, the company intends to use the funds to advance its clinical pip... |
| Dec 2, 2021 | SOTIO Secures €280m of Funding to Expand and Advance Clinical Pipeline | PPF Group provides funding to advance SOTIO through key clinical milestones
Proceeds shall be used to conduct two phase 2 studies with SOT101, including a checkpoint inhibitor combination trial Three programs (SOT102, BOXR1030, and SOT201) ... |
| Nov 18, 2021 | SOTIO Strengthens its Strategic Advisory Board with Esteemed Oncology Experts and Industry Veterans | PRAGUE, Czech Republic, Nov. 18, 2021 (GLOBE NEWSWIRE) -- SOTIO Biotech, a clinical stage immune-oncology company owned by PPF Group, announced the addition of three world-renowned clinical oncology research experts and biotechnology busine... |
| Nov 16, 2021 | SOTIO Expands its Antibody-Drug Conjugate Pipeline with Exclusive Collaboration and License Agreement with LegoChem Biosciences | SOTIO Biotech licenses LegoChem Biosciences (LCB) technology for five new antibody-drug conjugate (ADC) programs
Rights to LCB’s ADC platform acquired for total of up to $1027.5 million payable based on certain developments and regulatory a... |
| Nov 16, 2021 | SOTIO Expands its Antibody-Drug Conjugate Pipeline with Exclusive Collaboration and License Agreement with LegoChem Biosciences | SOTIO Biotech licenses LegoChem Biosciences (LCB) technology for five new antibody-drug conjugate (ADC) programs
Rights to LCB’s ADC platform acquired for total of up to $1027.5 million payable based on certain dvelopments and regulatory ac... |
| Nov 12, 2021 | SOT101 Shows Clinical Benefit in Patients with Advanced Solid Tumors | Majority of patients receiving SOT101 (SO-C101) + pembrolizumab had confirmed clinical benefit
Clinical responses have been observed in patients progressing on previous anti-PD-1 treatment
SOT101 monotherapy and in combination with pembroli... |
| Nov 3, 2021 | SOTIO to Present New Data from Phase 1 Study of IL-15 Superagonist, SOT101, at the Society for Immunotherapy of Cancer (SITC) 36th Annual Meeting | SOTIO will present three posters discussing data that highlight the encouraging safety and efficacy for SOT101 (SO-C101) as a monotherapy and in combination with pembrolizumab for the treatment of advanced solid tumors
BASEL, Switzerland, N... |
| Nov 7, 2019 | SOTIO expands collaboration with NBE Therapeutics | |
| Nov 7, 2019 | SOTIO exercises second target option under existing collaboration with NBE-Therapeutics to develop next-generation antibody-drug conjugates | Basel, Switzerland & Prague, Czech Republic – November 7, 2019 – NBE-Therapeutics AG and SOTIO a.s. today announced that SOTIO has elected a second target for the development of a next generation antibody-drug conjugate (ADC) under thei... |
| Nov 1, 2016 | New partner and investor for NBE Therapeutics | |
| Targovax and SOTIO announce first patient dosed in Phase I/II combination trial of ONCOS-102 with DCVAC | Oslo, Norway, 12 July 2018 – Targovax ASA (OSE: TRVX), a clinical stage company focused on developing and commercializing immune activators to target hard to treat solid tumors, and SOTIO, a biotechnology company owned by the PPF Group, ann... |