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| Oct 16, 2026 | Sobi receives positive CHMP opinion for TRYNGOLZA® (olezarsen) for the treatment of severe hypertriglyceridemia (sHTG) | Sobi receives positive CHMP opinion for TRYNGOLZA® (olezarsen) for the treatment of severe hypertriglyceridemia (sHTG)
Fri, Oct 16, 2026 12:45 CET Report this content
Positive CHMP opinion based on Phase 3 CORE and CORE2 results, demonstrat... |
| Oct 1, 2026 | NICE issues final draft guidance recommending ▼ Tryngolza® (olezarsen) as an option to treat genetically confirmed familial chylomicronaemia syndrome (FCS) in adults in England and Wales | FOR UK HEALTHCARE/TRADE MEDIA ONLY
Sobi® UK today announced that the National Institute for Health and Care Excellence (NICE) has issued final draft guidance which recommends Tryngolza® (olezarsen) as an option to treat genetically confirme... |
| Aug 9, 2026 | This teen once suffered hundreds of seizures a day. Now he can walk thanks to an experimental drug. | Getting your Trinity Audio player ready...
Connor Dalby could not walk for the first 14 years of his life, so his newfound ability to scamper down hallways is miraculous on its own.
But the experimental drug that reduced his severe and freq... |
| May 28, 2026 | Experimental hepatitis B drug may offer ‘functional cure’ for some patients | Getting your Trinity Audio player ready...
By LAURAN NEERGAARD, AP Medical Writer
WASHINGTON (AP) — A first-of-its-kind drug for hepatitis B is letting some patients stop treatment without showing signs of the dangerous liver virus, what’s ... |
| May 26, 2026 | New analysis shows Tryngolza® (olezarsen) reduced acute pancreatitis by 85% and triglycerides by 66% in severe hypertriglyceridemia | New analysis shows Tryngolza® (olezarsen) reduced acute pancreatitis by 85% and triglycerides by 66% in severe hypertriglyceridemia
Tue, May 26, 2026 16:15 CET Report this content
Sobi® (STO: SOBI) today announced results from a new analysi... |
| Mar 30, 2026 | EMA validates indication extension application for Tryngolza® (olezarsen) for the treatment of severe hypertriglyceridemia (sHTG) | EMA validates indication extension application for Tryngolza® (olezarsen) for the treatment of severe hypertriglyceridemia (sHTG)
Mon, Mar 30, 2026 08:00 CET Report this content
Sobi® (STO: SOBI) today announced that the European Medicines ... |
| Feb 20, 2026 | Curt Smith: Fighting blood cancer is easier with a group effort | |
| Jan 30, 2026 | This 11-year-old has battled a rare disease for years — a breakthrough drug helped deliver relief | To share your story, or find out how to get involved with CNBC Cures, email [email protected]
Susannah Rosen was diagnosed with a KIF1A gene mutation at the age of 2½.
Patients diagnosed with severe KIF1A gene mutations may live only into... |
| Nov 8, 2025 | Clinically meaningful pivotal study results for olezarsen in sHTG presented as a late breaker at AHA Scientific Sessions | Clinically meaningful pivotal study results for olezarsen in sHTG presented as a late breaker at AHA Scientific Sessions
Sat, Nov 08, 2025 15:40 CET Report this content
Sobi® (STO: SOBI) today announced that, the TIMI Study Group today has ... |
| Sep 19, 2025 | Tryngolza ® (olezarsen) approved in the European Union for familial chylomicronemia syndrome (FCS) | Tryngolza ® (olezarsen) approved in the European Union for familial chylomicronemia syndrome (FCS)
Fri, Sep 19, 2025 08:00 CET Report this content
Sobi® (STO: SOBI), a global biopharmaceutical company dedicated to delivering innovative trea... |
| Jul 25, 2025 | TRYNGOLZA® (olezarsen) recommended for EU approval by CHMP for familial chylomicronemia syndrome (FCS) | TRYNGOLZA® (olezarsen) recommended for EU approval by CHMP for familial chylomicronemia syndrome (FCS)
Fri, Jul 25, 2025 13:15 CET Report this content
Recommendation based on Phase 3 Balance results, which showed a significant reduction of ... |
| Nov 18, 2024 | ExeVir Announces Michael Garrett as New CEO | ExeVir Bio, a Ghent, Belgium-based biotech company developing heavy chain-only antibodies targeting highly conserved epitopes for broad protection against infectious diseases, announced the appointment of Michael Garrett as its new Chief Ex... |
| Jul 10, 2024 | BOLDEN THERAPEUTICS TO PRESENT AT THE 4TH ANNUAL OLIGONUCLEOTIDES FOR CNS SUMMIT | PROVIDENCE, R.I., July 10, 2024 /PRNewswire/ -- Bolden Therapeutics, Inc., a biotechnology company developing first-in-class therapeutics to promote neurogenesis for the potential treatment of CNS illnesses, today announced their invitation... |
| Mar 6, 2024 | New Biomarker Data Add Further Evidence Supporting the Potential Benefit of SPINRAZA® (nusinersen) in Infants and Toddlers with Unmet Clinical Needs after Gene Therapy | |
| Jan 22, 2024 | Investigators fault Lilly plant for manufacturing issues | Want to stay on top of the science and politics driving biotech today? Sign up to get our biotech newsletter in your inbox.
Today, lots of regulatory content! We talk about march-in rights and chastening TikTok influencers for their prescri... |
| Dec 22, 2023 | Wainua (eplontersen) granted first US FDA approval | Wainua (eplontersen) granted first US FDA approval
Fri, Dec 22, 2023 08:00 CET Report this content
22 December 2023
Wainua (eplontersen) granted first-ever regulatory approval in the US for the treatment of adults with polyneuropathy of her... |
| Sep 7, 2022 | Ionis, AstraZeneca going to FDA with PhIII data in hand; Glaukos touts double PhIII win in eye implant | Ionis and AstraZeneca are hoping its latest results net an FDA approval.
The two companies presented their latest Phase III results from a 35-week analysis of the Phase III trial, dubbed NEURO-TTRansform, of AstraZeneca’s ... |
| Jun 21, 2022 | Eplontersen Ph III trial met co-primary endpoints | Eplontersen Ph III trial met co-primary endpoints
Tue, Jun 21, 2022 08:11 CET Report this content
21 June 2022 07:00 BST
Eplontersen met co-primary and secondary endpoints in interim analysis of the NEURO-TTRansform Phase III trial for here... |
| Jan 31, 2022 | Pfizer and Ionis announce discontinuation of vupanorsen clinical development program | NEW YORK and CARLSBAD, Calif., Jan. 31, 2022 /PRNewswire/ -- Pfizer Inc. (NYSE: PFE) and Ionis Pharmaceuticals, Inc. (NASDAQ: IONS) today announced the discontinuation of the Pfizer-led clinical development program for vupanorsen (PF-072855... |
| Jan 31, 2022 | Pfizer and Ionis announce discontinuation of vupanorsen clinical development program | NEW YORK and CARLSBAD, Calif., Jan. 31, 2022 /PRNewswire/ -- Pfizer Inc. (NYSE: PFE) and Ionis Pharmaceuticals, Inc. (NASDAQ: IONS) today announced the discontinuation of the Pfizer-led clinical development program for vupanorsen (PF-072855... |
| Sep 3, 2021 | Ionis to host ATTR symposium highlighting CARDIO-TTRansform Study at 3rd European ATTR Amyloidosis meeting | |
| Aug 4, 2021 | Ionis Pharmaceuticals : 2Q21 Earnings Slides | Q2 2021 Financial
Results and Business
Update
August 4, 2021
On Today's Earnings Call
Brett Monia, Ph.D. Beth Hougen Richard Geary, Ph.D.
Chief Executive Officer Chief Financial Officer Executive Vice President, Development
Eric Swayze, Ph.... |
| Aug 4, 2021 | Ionis reports second quarter 2021 financial results and recent business achievements | |
| Aug 2, 2021 | Lp(a) HORIZON achieves 50% enrollment in trial to assess the safety and efficacy of pelacarsen in reducing recurrent cardiovascular events | |
| Jun 14, 2021 | Ionis' Chief Scientific Officer C. Frank Bennett, Ph.D., receives Gabbay Award in Biotechnology and Medicine | |
| Jun 10, 2021 | Ionis' antisense therapies in ATTR amyloidosis to be featured at 2021 PNS Annual Meeting | |
| Jun 2, 2021 | Ionis announces changes to its board of directors at annual meeting of stockholders | |
| May 28, 2021 | BB Biotech : investment trust review highlights long t... | Launched in 1993, BB Biotech (BION) is one of the largest specialist funds investing in the fast-growing sector of
biotechnology. It is managed by Bellevue Asset Management, a healthcare investment manager headquartered in Switzerland, and ... |
| Apr 6, 2021 | Nearly 70% of Akcea's workforce is on the chopping block as Ionis executes major restructuring | About half a year after reabsorbing its lipid-focused spinout Akcea, Ionis is now putting a major reorganization plan in play — one that involves shaving nearly 70% of the subsidiary’s workforce and expanding its distr... |
| Apr 6, 2021 | Ionis announces proposed private placement of convertible notes | |
| Mar 1, 2021 | Ionis establishes new grant program to advance research and understanding of transthyretin amyloidosis | |
| Nov 30, 2020 | Ionis announces AstraZeneca's initiation of the Phase 2b clinical study of its antisense medicine targeting PCSK9 to lower LDL-cholesterol | |
| Nov 23, 2020 | Ionis announces third investigational antisense medicine to treat nonalcoholic steatohepatitis (NASH) enters development | |
| Oct 12, 2020 | Ionis Pharmaceuticals completes acquisition of Akcea Therapeutics | |
| Oct 1, 2020 | Ionis Chief Scientific Officer Frank Bennett receives Lifetime Achievement Award from Oligonucleotide Therapeutics Society | |
| Sep 30, 2020 | Ionis treatment for Alexander disease receives orphan drug designation from U.S. FDA | |
| Aug 31, 2020 | Ionis Pharmaceuticals to acquire remaining stake in Akcea Therapeutics | |
| Dec 27, 2019 | Ionis Pharmaceuticals has agreed to license one of its Alzheimer’s research programs to longtime partner, Biogen, in a deal valued at up to $200M | |
| Oct 15, 2019 | BridgeBio terminates effort to acquire remainder of Eidos Therapeutics | Eidos trades publicly on the Nasdaq, and its shares fell 6.5 percent Monday morning following the news, remaining down 3.1 percent Tuesday afternoon. BridgeBio’s shares were up 2 percent.
The subsidiary, which is headquartered in San Franci... |
| Aug 27, 2019 | GSK licenses Ionis' experimental hep B treatments in up to $262M deal | GSK $GSK may have walked away from two of Ionis’ $IONS antisense drugs (including the now-approved Tegsedi) in 2017 — but the British drugmaker held on as a partner to the biotechnology company’s experimental hepatitis... |
| Apr 20, 2018 | Biogen pays $1B cash to enlist Ionis on a new drug discovery campaign — but can it deliver fast enough for analysts? | Looking to build up its pipeline, Biogen $BIIB is going back to the partner that provided it with its last big hit, Spinraza.
In a new discovery alliance announced early Friday, Biogen has agreed to pay $1 billion cash for e... |
| Nov 10, 2017 | Celgene's Michael Pehl leaps up to lead role at Immunomedics; GSK nabs Hal Barron to helm R&D; Aimmune CEO to step down | Michael Pehl
→ Michael Pehl will take the top job at Immunomedics next month after 11 years at Celgene, where he was most recently head of hematology and oncology. As president and CEO, his priority will be pushing for the a... |
| Nov 7, 2017 | Mumbai-based Lupin gets FDA warning for two manufacturing sites; Ionis promotes inotersen head as new COO | → Indian drug manufacturer Lupin received a warning letter from the FDA claiming that it had violated good manufacturing practices, the company disclosed in a filing to the Bombay Stock Exchange. Two facilities in... |
| Oct 13, 2017 | Ionis launches an early-stage tau drug study for Alzheimer’s, picking up $10M from Biogen | After amyloid beta, the second big target in Alzheimer’s disease centers on toxic accumulations of tau, possibly working hand-in-hand with a-beta to fry people’s memories. And today Ionis $IONS says that it’s picking ... |
| Aug 17, 2017 | EuroBiotech Report—Mullen backs Vicarius, GlaxoSmithKline jilts Ionis, CellAct lands $250M deal and data on Sanofi diabetes pill | Welcome to the latest edition of our weekly EuroBiotech Report. We start this week in Switzerland, where a clutch of ex-Biogen leaders has hatched an ambitious plan to provide U.S. biotechs with a new way to bring drugs to market in Europe.... |
| Jan 6, 2017 | Novartis adds to its cardio pipeline with $1.65B Ionis pact | Akcea CEO Paula Soteropoulos
Novartis is making a big bet on two of Ionis’ cardio drugs.
The pharma giant $NVS is handing over $225 million in near-term payments, split between fees, an upfront and an equity stake, and promi... |
| Feb 12, 2016 | Should you take a genetic test? Here’s what expert counselors advise | If you could take a genetic test to find out if you had an elevated risk of a deadly disease, would you? Should you? And if you did, how would you deal with the results?
Those are questions that genetic counselors and patient advocates deal... |
| BridgeBio terminates effort to acquire remainder of Eidos Therapeutics | A firm that helps launch biomedical research into new companies has called off a bid to acquire one of its subsidiaries.
Palo Alto, California-based BridgeBio Pharma said Monday that it had terminated a merger process with subsidiary Eidos ... |
| Добро пожаловать в Карлсбад: Как город в США привлекает стартаперов морем, пляжами и прекрасной погодой | Город Карлсбад в Южной Калифорнии решил, что ему нужны не только туристы, но еще и молодые предприниматели. Их приглашают приезжать с собственными командами и оставаться надолго, чтобы работать в идеальном климате и разбавлять трудовые будн... |
| Cancer doc: To boost minority participation, we have fliers in our clinic saying “Ask me about a clinical trial” | To drive diverse participation in precision medicine efforts, providers and patient advocacy groups must identify and break down the barriers that exclude minority communities — beginning with the lack of awareness.
Actively encouraging min... |