While current treatment approaches focus on increasing exercise, decreasing food intake, and increasing insulin, Adipo believes there is another option. Our promise to the millions of people living with obesity and diabetes is to transform the management of their disease by changing energy-storing white fat into energy-burning brown fat. Transformation of adipose tissue through browning has the potential to use the body’s own physiology to raise energy expenditure, reduce adiposity and improve insulin resistance.
To accomplish this, we are developing an innovative technology platform of localized, polymer-based nanoparticulate delivery of Notch inhibitors to induce white adipocyte browning in specific fat depots. The physiological effects of the newly formed brown adipose tissue will drive greater energy expenditure and improved insulin sensitivity. Adipo’s innovative therapy combines the recent discovery of the role played by Notch signaling in adipocyte browning, with advances in polymer-based drug delivery to minimize the risk of systemic toxicity. Adipo’s treatment offers the potential of a unique value proposition for the treatment of obesity and diabetes, providing sustainable weight loss, improved glucose control and systemic metabolism, with minimized off-target side effects.
Location: United States, Indiana, West Lafayette
Employees: 1-10
Founded date: 2017
Investors 1
Date | Name | Website |
- | VisionTech... | visiontech... |
Mentions in press and media 6
Date | Title | Description | Source |
27.10.2023 | As Money for Female-Led Startups Tightens, VisionTech Angels... | Female founders reading a TechCrunch report in mid-July found little to smile about. The media outle... | visiontech... |
18.04.2023 | VisionTech Angels Invest $242,000 in Indiana-Based Adipo The... | INDIANAPOLIS, Indiana (April 11, 2023) – – VisionTech Angels, among the Midwest’s most active angel ... | visiontech... |
28.10.2022 | Meet October Pitch Presenter #1: Karen Wurster of Adipo Ther... | I first met Karen Wurster, CEO of Adipo Therapeutics, a year ago when she first pitched the VisionTe... | visiontech... |
- | As Money for Female-Led Startups Tightens, VisionTech Angels... | Female founders reading a TechCrunch report in mid-July found little to smile about. The media outle... | visiontech... |
- | Meet October Pitch Presenter #1: Karen Wurster of Adipo Ther... | I first met Karen Wurster, CEO of Adipo Therapeutics, a year ago when she first pitched the VisionTe... | visiontech... |
- | VisionTech Angels Invest $242,000 in Indiana-Based Adipo The... | INDIANAPOLIS, Indiana (April 11, 2023) – – VisionTech Angels, among the Midwest’s most active angel ... | visiontech... |