Accelero Biostructures

Accelero Biostructures accelerates structure-based drug discovery and protein engineering using its Synchrotron-integrated platform for High-Throughput Protein X-ray Crystallography. With a 15-year track record, we are geared toward structure-based drug discovery for pharmaceutical/biotechnology, structure-based protein engineering for industrial enzymes, and academic drug discovery and structural biology projects.

We capitalize on 15 years of HT protein x-ray crystal structure determination at the Joint Center for Structural Genomics (JCSG) headed by Prof. Ian A. Wilson at The Scripps Research Institute, La Jolla; Genomics Institute of the Novartis Foundation, La Jolla; Sanford-Burnham Medical Research Institute, La Jolla; and SLAC National Accelerator Laboratory, Menlo Park, with investments from the National Institutes of Health-National Institute of General Medical Sciences'​ Protein Structure Initiative and considerable investments from participating institutions. JCSG developed a robust gene to structure pipeline.

A multi-institutional, industry-like operation with distributed clients was established. The primary drivers were efficiency and cost. More than 1500 novel protein structures were solved, resulting in over 300 publications.

Accelero Biostructures has a wealth of experience with proven productivity, with a team of highly trained protein crystallographers with more than 40 years total training and experience at top structural biology laboratories. You can rely on us to provide you with superior protein crystallography and structural biology services.