Hyro Secures $45 Million to Advance Healthcare AI

October 22, 2025, 9:38 pm
Prisma Health
Prisma Health
HealthTechMedtechNonprofit
Location: United States, South Carolina, Greenville
Employees: 10001+
Founded date: 2017
Total raised: $200K
Sutter Health
Sutter Health
BusinessCareContentHealthTechInformationITMediaMedTechPersonalSocial
Location: United States, California, Sacramento
Employees: 10001+
Founded date: 1918
Total raised: $110M
ServiceNow
ServiceNow
Location: United States, California, Santa Clara
Employees: 10001+
Founded date: 2004
Hyro, a leader in responsible AI agents for healthcare, raised $45 million. This strategic growth funding doubles its valuation, bringing total capital to $95 million. The investment empowers Hyro to expand its cutting-edge platform. Its hybrid AI, combining LLMs and specialized SLMs, automates up to 85% of routine patient interactions. This includes scheduling, registration, and prescription management. The system ensures HIPAA compliance and deep integration with EHRs. It helps over 45 health systems, reaching 30 million patients. Hyro tackles staffing shortages, enhances patient access, and boosts operational efficiency. This funding solidifies AI's critical role in modern healthcare. It fuels innovation and wider adoption of enterprise-ready AI solutions, addressing critical industry demands for digital-first patient experiences.

A significant investment reshapes healthcare technology. Hyro, a prominent AI agent platform, recently announced a $45 million strategic growth round. This infusion of capital positions Hyro as a driving force in healthcare automation. The funding swiftly follows a previous raise, doubling the company's valuation. Total capital now stands at an impressive $95 million.

Healthier Capital led the round. Norwest and Define Ventures also participated. Existing investors demonstrated continued confidence. Strategic partners Bon Secours Mercy Health and ServiceNow Ventures joined the initiative. This diverse investor base underscores industry trust in Hyro’s vision.

Hyro focuses on responsible AI. Its platform delivers AI agents tailored for healthcare systems. These agents simplify patient access and enhance operational efficiency. They operate across digital and voice channels. Call centers, websites, SMS, and mobile apps all benefit.

The core problem Hyro solves is complex. Healthcare systems face immense pressures. Staffing shortages persist. Operational constraints burden providers. Patients demand real-time access and digital-first experiences. Hyro's AI solutions directly address these critical challenges.

Hyro’s technology stands apart. It employs a sophisticated hybrid approach. Large Language Models (LLMs) form a powerful base. Proprietary conversational engines augment them. Crucially, healthcare-specific Small Language Models (SLMs) integrate into the system. Advanced knowledge graphs, built for medical contexts, complete the architecture.

This unique combination yields exceptional results. Hyro’s AI agents autonomously manage a high volume of routine interactions. They resolve up to 85% of these common tasks. Functions include patient registration, intelligent routing, appointment scheduling, and prescription management. This frees human staff for more complex cases.

Data security and privacy are paramount in healthcare. Hyro’s platform adheres to strict standards. It maintains full HIPAA compliance. Deep interoperability with existing tech stacks is another key feature. EHRs like Epic integrate seamlessly. Leading CRM systems connect effortlessly. Secure API calls facilitate this integration.

The AI agents pull relevant patient data. They perform tasks like booking appointments or refilling prescriptions. When human intervention becomes necessary, the system transitions smoothly. A seamless contextual transfer ensures continuity of care. Live human agents receive complete information. This enhances support, it does not replace it.

Operational impact is substantial. Health systems achieve significant returns on investment. Efficiency skyrockets. Patient access improves dramatically. The administrative burden on staff lessens. This translates into better resource allocation.

Hyro’s reach is extensive. Over 45 leading health systems currently deploy its platform. Esteemed clients include Sutter Health, Tampa General Hospital, Prisma Health, and Piedmont Healthcare. Intermountain Health, Baptist Health, and Hackensack Meridian Health also leverage Hyro’s solutions.

Millions of patients benefit daily. Over 30 million individuals in the U.S. engage with Hyro’s conversational AI. Payers and specialty clinic groups increasingly adopt the technology. This broad adoption signifies proven real-world value.

The company constantly innovates. Its latest offering, Proactive Px, exemplifies this. Proactive Px broadens the platform’s capabilities. It supports bi-directional, omnichannel communication. Health systems can now proactively engage patients across inbound and outbound touchpoints. This elevates patient experience.

Visibility into performance is vital. All interactions are tracked and visualized. Hyro’s Patient Intelligence Dashboard provides real-time metrics. Clients gain insights into conversational performance. Operational impact and AI agent efficacy are clearly displayed. This data-driven approach allows continuous optimization.

The new funding has clear objectives. Hyro plans to accelerate adoption across additional healthcare segments. This means expanding its market reach. It also involves deepening integration within existing provider networks. Product innovation remains a core focus. The goal is to evolve the suite of administrative, operational, and clinical AI agents.

Founded in 2018 by Israel Krush and Rom Cohen, Hyro has grown rapidly. Its consistent execution has secured enterprise customers. Expanding relationships with existing clients further solidifies its market position. The company focuses on patient-ready, enterprise-ready AI agents. These are designed around proven workflows and best practices.

The investment reflects a broader industry trend. Healthcare organizations increasingly recognize the value of responsible, enterprise-grade AI solutions. The shift towards digital-first care experiences is irreversible. AI agents provide a scalable solution to meet patient demands and overcome operational hurdles.

Hyro's hybrid architecture differentiates it from newer AI startups. It provides a robust, safe, and effective platform. Polished chatbots are insufficient for complex healthcare needs. Integration with EHRs, CRMs, and clinical workflows is essential. Hyro delivers this at scale.

The company is poised for significant expansion. It will likely expand across new specialties and segments within the healthcare ecosystem. Its approach is built on trust and tangible impact. This funding round reinforces that commitment. Hyro continues to define the future of AI communications in healthcare. Its journey marks a pivotal moment for medical technology.