AusperBio Secures $63 Million for Targeted Hepatitis B Cure

September 26, 2025, 10:03 pm
CDH Investments
CDH Investments
Employees: 201-500
Founded date: 2002
AusperBio
BiotechnologyClinicalStageHepatitisOligonucleotidesTherapeutics
Location: United States
Total raised: $123M
Qiming Venture Partners
Qiming Venture Partners
ServiceHealthTechPlatformTechnologyMedTechProductDevelopmentDrugResearchProvider
Location: China, Shanghai
Employees: 51-200
Founded date: 2006
AusperBio, a clinical-stage biotechnology firm, closed a $63 million Series B2 funding round. This substantial capital infusion will accelerate its mission. The company develops targeted oligonucleotide therapies. Its lead candidate, AHB-137, targets chronic hepatitis B. Funds will drive AHB-137 through pivotal and multiple Phase II global clinical trials. The investment also supports expanding AusperBio's innovative Med-Oligo ASO platform. This platform is key to developing advanced drug candidates. Investors, including Qiming Venture Partners, showed strong confidence. This backing fuels the pursuit of a functional cure. It addresses a critical global health need. AusperBio strengthens its pipeline and manufacturing capabilities. The firm is positioned for significant progress in transformative medicine.

AusperBio secured substantial new capital. The biotechnology firm announced a $63 million Series B2 funding round. This significant investment fuels its clinical development goals. It accelerates progress on targeted oligonucleotide therapies. The company targets one of the world’s most persistent viral diseases. Chronic hepatitis B remains a major global health challenge. This fresh funding propels AusperBio’s mission forward. It aims for a functional cure. This commitment underscores investor confidence. They see immense promise in AusperBio’s innovative approach. Such backing is critical for cutting-edge biotech.

The primary focus for these funds is AHB-137. This is AusperBio’s lead product candidate. AHB-137 advances toward a functional cure for chronic hepatitis B. The capital will push AHB-137 through critical trials. This includes a pivotal study. Such studies are crucial for regulatory approval. Multiple Phase II combination trials are also planned. These explore optimal treatment regimens. Expanding global Phase II development is a key objective. This strategic move brings the treatment closer to patients worldwide. It marks a significant step in drug development. AHB-137 is poised to become a foundational therapy. It offers strong potential as a backbone treatment component. Early data reinforces its promise.

AusperBio operates on a proprietary foundation. It developed the Med-Oligo ASO platform. This platform is central to its therapeutic strategy. It substantially enhances existing ASO therapeutics. Novel insights guide its design. These include refined chemistry and targeting mechanisms. The platform combines efficient targeted delivery. This conjugation technology is crucial. It ensures drugs reach specific disease sites. This minimizes off-target effects. It also improves therapeutic efficacy. It empowers ASO therapeutics to treat a broad range of diseases. This extends beyond viral infections like hepatitis B. It includes metabolic conditions. Genetic disorders and immune diseases are also targets. This broad applicability highlights the platform’s immense potential. It represents a paradigm shift in precision medicine. It leverages the power of genetic modulation.

Chronic hepatitis B affects millions globally. Estimates suggest over 290 million people live with the infection. It causes severe liver damage. Cirrhosis and liver cancer are common, often fatal, outcomes. Current antiviral therapies manage the virus. They suppress viral replication. They rarely achieve a functional cure. This leaves a vast unmet medical need. Patients face lifelong medication. They endure continuous health monitoring. New, more effective treatments are desperately required. AusperBio directly addresses this urgent necessity. Its ambition is to transform patient outcomes. A functional cure means sustained viral suppression. It means clearing HBsAg. It means improved quality of life. It offers a future free from lifelong medication. This would ease immense personal and public health burdens. It represents a monumental step in global health.

The funding round saw strong participation. Qiming Venture Partners co-led the investment. A globally recognized strategic investor also joined. This diversified backing signals broad industry support. Existing investors reaffirmed their belief. HanKang Capital, CDH Investments, YuanBio Venture Capital, Sherpa Capital, and Genesis Capital participated. Their continued involvement is noteworthy. It reflects deep faith in AusperBio’s scientific progress. It validates the commercial potential of its pipeline. The capital infusion reinforces the company's financial strength. It secures resources for aggressive growth. This collective investment underscores market confidence in targeted oligonucleotide therapies. It recognizes the urgency of new chronic hepatitis B solutions.

AusperBio maintains its private status. It remains a clinical-stage biopharmaceutical company. Its operations span the USA and China. This dual presence supports global development. It facilitates access to diverse patient populations. The company dedicates itself to advancing oligonucleotide technologies. Targeted delivery systems are paramount. These form the core of its transformative therapies. Beyond AHB-137, the funding supports pipeline expansion. It will scale up manufacturing partnerships. These preparations ensure long-term growth. They secure supply for future market demands. AusperBio positions itself as a leader. It aims to deliver functional cures for multiple diseases. This ambitious vision drives its research and development. It promises new hope for countless patients. The company’s trajectory points to significant future milestones. Its innovative approach could redefine chronic disease management. This funding round empowers that critical journey. It moves biotechnology closer to a global health breakthrough.