Pairwise: Cultivating the Future of Agriculture with Gene Editing

September 17, 2024, 9:33 pm
Pairwise
Pairwise
AgriTechB2CBuildingBusinessFoodTechProductTechnology
Location: United States, North Carolina, Durham
Employees: 51-200
Founded date: 2018
Total raised: $130M
Corteva Agriscience
Corteva Agriscience
AgriTechFoodTechIndustryLocalPageProductProductivityServiceSoftwareTools
Location: United States, Delaware, Wilmington
Employees: 10001+
Founded date: 2018
In the heart of Durham, North Carolina, a revolution is brewing. Pairwise, a technology company at the forefront of gene editing, has just secured $40 million in Series C funding. This latest round, led by Deerfield Management, pushes their total funding to a staggering $155 million. With new partners like Corteva, the stakes are high, and the potential is enormous.

Pairwise is not just another startup. It’s a beacon of innovation in agriculture. The company specializes in gene editing, a technique that allows scientists to make precise changes to a plant's DNA. Think of it as a sculptor chiseling away at a block of marble, revealing the masterpiece within. This technology aims to enhance plant breeding, making crops more resilient, nutritious, and appealing to consumers.

The funding will fuel agricultural research and development, focusing on sustainable food production. Pairwise plans to expand its product pipeline and enhance its Fulcrum™ platform, a suite of advanced gene editing tools. This platform is akin to a Swiss Army knife for geneticists, offering various methods to create new plant varieties.

One of the standout innovations from Pairwise is its seedless blackberry. This fruit promises a better eating experience, free from the hassle of seeds. It’s not just about convenience; it’s about creating a product that benefits everyone involved—from consumers to farmers. The blackberry is designed with compact architecture and thornless traits, making it easier to grow and harvest. This is a win-win for both the environment and the agricultural workforce.

But the excitement doesn’t stop there. Pairwise has formed a five-year joint venture with Corteva, a giant in the agtech sector. This collaboration aims to harness gene editing to enhance climate resilience in staple crops like corn and soybeans. Imagine a world where crops can withstand droughts and pests with ease. This partnership could make that vision a reality.

Gene editing, particularly through CRISPR technology, is often described as “programmable DNA scissors.” This metaphor captures its essence perfectly. Scientists can target specific genes, making precise edits without introducing foreign DNA. This is a game-changer in agriculture, where traditional breeding methods can be hit-or-miss. With gene editing, the randomness is reduced, allowing for more predictable outcomes.

Pairwise is not alone in this endeavor. The company collaborates with industry leaders like Bayer and Corteva, gaining access to vast agricultural landscapes. This partnership opens doors to hundreds of millions of acres where their technology can be applied. The implications are profound. With the right tools, Pairwise can address pressing agricultural challenges, from improving yields to enhancing nutritional profiles.

The regulatory landscape for gene editing is evolving. In many regions, including the Americas, policies are becoming more favorable. Countries like China and Japan have already embraced gene-edited crops, while Europe is slowly shifting its stance. This changing tide could pave the way for broader acceptance of gene editing as a legitimate breeding tool rather than a controversial GMO technology.

Pairwise’s innovations extend beyond just convenience. The company is focused on enhancing the nutritional value of crops. For instance, they are working on mustard greens that retain their nutritional benefits while eliminating bitterness. This approach not only makes the greens more palatable but also encourages healthier eating habits.

Moreover, Pairwise is exploring the domestication of native plants, such as black raspberries. These berries are more nutritious than their red counterparts but come with challenges like large seeds. By using CRISPR, Pairwise aims to create a version that combines the best traits of both varieties. This is akin to finding a hidden treasure and polishing it until it shines.

The potential applications of gene editing in agriculture are vast. From creating drought-resistant crops to enhancing flavor profiles, the possibilities are endless. Pairwise is at the forefront of this transformation, armed with cutting-edge technology and a vision for a sustainable future.

As climate change continues to pose challenges to global food security, innovations like those from Pairwise become increasingly vital. The world needs solutions that can adapt to shifting conditions, and gene editing offers a pathway to resilience. By collaborating with industry giants and leveraging advanced technologies, Pairwise is positioning itself as a leader in the agricultural revolution.

In conclusion, Pairwise is not just cultivating crops; it’s cultivating hope. With its recent funding and strategic partnerships, the company is poised to make a significant impact on the future of agriculture. As they harness the power of gene editing, the dream of a more sustainable, nutritious, and resilient food system is within reach. The seeds of change have been planted, and the harvest promises to be bountiful.