Seegene's New PCR Tests: A Shield Against Mpox

August 29, 2024, 2:04 am
Seegene Inc
DiagnosticsFuture
Location: South Korea, Seoul
Employees: 501-1000
Founded date: 2000
In the world of infectious diseases, time is of the essence. The quicker we can identify a threat, the better our chances of containment. Seegene Inc., a South Korean leader in molecular diagnostics, has stepped up to the plate. With the resurgence of mpox, a viral disease that once seemed to be under control, Seegene has developed two new PCR test assays. These tests are designed to detect multiple viruses simultaneously, a crucial advancement in the fight against this global health threat.

The Novaplex™ MPXV/OPXV Assay and the Novaplex™ HSV-1&2/VZV/MPXV Assay are the latest tools in Seegene's arsenal. They utilize multiplex PCR technology, allowing for the detection of four viruses at once. This is like having a Swiss Army knife in the lab—one tool, multiple functions. Each assay is intended for research use only, but their implications are vast.

The need for such tests has never been more pressing. The World Health Organization (WHO) declared mpox a Public Health Emergency of International Concern (PHEIC) in August 2023. This declaration came after a worrying spike in cases, particularly driven by Clade 1b, a variant known for its increased transmissibility and higher mortality rate. The urgency is palpable. Countries are scrambling to ensure they have the necessary tools to combat this virus.

Seegene's assays are designed to meet this need head-on. The Novaplex™ MPXV/OPXV Assay focuses on detecting Orthopox viruses, including both Clades 1 and 2 of the mpox virus. Early detection is critical, especially given mpox's long incubation period of up to 21 days. The ability to differentiate between these clades can provide invaluable information for public health responses.

The second assay, Novaplex™ HSV-1&2/VZV/MPXV, expands the scope even further. It not only detects mpox but also identifies herpes simplex viruses and varicella-zoster virus. This broad coverage is essential, as symptoms can overlap, making accurate diagnosis a challenge. By using multiplex PCR testing, these assays can provide reliable results while saving time and resources.

Both assays incorporate dual internal controls. This means that every test validates itself, ensuring the integrity of the sample and the testing process. It’s like having a safety net; even if something goes wrong, the controls will catch it. This feature is crucial for maintaining trust in diagnostic results, especially in a time of crisis.

The mpox virus is not new. It has been endemic in parts of Africa for years. However, its recent global spread has raised alarms. The symptoms, primarily a pustular rash, can be severe and disfiguring. The WHO's declaration in July 2022 marked the beginning of heightened awareness. As cases surged again in 2023, the urgency for effective testing became clear.

Seegene is not just reacting; it is proactively addressing the needs of various countries. The company has pledged to collaborate with governments worldwide to ensure that these assays reach those who need them most. This commitment is vital, especially for developing nations that may lack access to advanced medical technologies.

The landscape of infectious diseases is ever-changing. New variants emerge, and old ones resurface. The recent confirmation of a mutated mpox case in Sweden is a stark reminder of this reality. As the virus spreads beyond Africa to places like Pakistan, the Philippines, and Thailand, the global community must remain vigilant.

Seegene's experience in the field is noteworthy. With over 23 years of research and development, the company has honed its expertise in multiplex PCR technologies. During the COVID-19 pandemic, it provided over 340 million tests to more than 100 countries. This track record speaks volumes about its capabilities and commitment to public health.

In a world where diseases can spread like wildfire, having reliable testing is akin to having a fire extinguisher on hand. It allows for quick action and containment. Seegene's new assays are not just tests; they are a lifeline in the battle against mpox.

As we look to the future, the importance of rapid and accurate diagnostics cannot be overstated. The fight against infectious diseases is a marathon, not a sprint. With tools like Seegene's assays, we can better navigate the challenges ahead. The goal is clear: a world free from the shackles of disease.

In conclusion, Seegene's innovative approach to mpox testing represents a significant step forward. The combination of advanced technology, commitment to global health, and a proactive stance against emerging threats positions the company as a key player in the ongoing battle against infectious diseases. As we face new challenges, the importance of such advancements cannot be ignored. The fight against mpox is far from over, but with tools like these, we are better equipped to face it head-on.