The Column Group (TCG) is a science-driven venture capital firm that makes significant financial and operational commitments to build early stage drug discovery companies based on their unique scientific platforms and potential to deliver multiple breakthrough therapeutics.
TCG’s investment strategy runs counter to the prevailing trend in life sciences venture capital toward assembling diversified portfolios of later stage, single product-orientated companies across multiple industry sectors, with proximity to value inflection points and the early identification of a Pharma “buyer” as key investment considerations.
In contrast, TCG takes the long view in making investments, recognizing that significant time is often required to generate significant value. Our approach is not “building-to-exit.” Key variables, including scientific opportunities, the competitive and regulatory landscape, and Pharma priorities, can change very rapidly. Instead, TCG’s mission is the generation of fundamentally strong companies, built from the ground up based on great science and the ability to generate multiple differentiated product opportunities.
Rather than diversification, TCG emphasizes focus. We are dedicated to early stage drug discovery as the best source of a new generation of novel, highly effective human therapies. We believe that the most critical resources, such as great ideas, world class founders, and top quality managerial and scientific talent, are very rare and that concentrating them within a small cohort of companies is the key path to success.
TCG is about the bold pursuit of big ideas using innovative science to generate breakthrough therapies that address significant diseases. Our firm is committed to all facets of company building and brings together a rich combination of scientific, financial and operational expertise to shape promising science into a value-rich portfolio poised to have a profound impact on human health.
Location: United States, California, San Francisco
Employees: 11-50
Investment Type: Venture Capital
Investment Stage: Pre-Seed; Seed; Series A; Series D; Series E
Portfolio 28
Date | Name | Website | Total Raised | Location |
31.05.2023 | Carmot The... | carmot.us | $150M | United Sta... |
15.02.2022 | KALLYOPE | kallyope.c... | $479M | - |
07.10.2020 | A2 Biother... | a2biothera... | $71.5M | - |
28.07.2020 | NURA BIO | nurabio.co... | $73M | - |
17.07.2020 | Hexagon Bi... | hexagonbio... | $232.3M | United Sta... |
- | Eikon Ther... | eikontx.co... | $666M | United Sta... |
- | NURIX | nurix-inc.... | $145.1M | - |
- | NGM Biopha... | ngmbio.com | $101M | United Sta... |
- | Ribon Ther... | ribontx.co... | $155M | United Sta... |
- | Plexium | plexium.co... | $165M | United Sta... |
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News 18
Date | Title | Description |
27.09.2023 | Dr. Dan Nomura joins The Column Group as iPartner | The Column Group announced the recruitment of Dr. Dan Nomura to the firm’s renowned group of iPartne... |
16.08.2023 | Dr. Sarah Hymowitz Promoted from Venture Partner to Partner | Copyright © 2022. The Column Group | Privacy Policy | Terms of Use Website developed by CP Communica... |
16.08.2023 | Dr. Millie Ray Promoted from Principal to Partner | Copyright © 2022. The Column Group | Privacy Policy | Terms of Use Website developed by CP Communica... |
17.08.2022 | The Column Group Raises $1.23 Billion in Two New Funds | We are very excited to announce that we have closed the two newest funds of the TCG fund family – Th... |
03.05.2022 | Dr. Hui Tian joins The Column Group as Venture Partner | The Column Group announces the hiring of Dr. Hui Tian. Previously, Dr. Tian was a founding member of... |
25.11.2021 | Mr. Jeff Goater joins The Column Group as Venture Partner | The Column Group announces the hiring of Mr. Jeff Goater. Previously, Mr. Goater served as Chief Exe... |
25.11.2021 | Dr. Sarah Gillmor Hymowitz joins The Column Group as Venture... | The Column Group announces the hiring of Dr. Sarah Gillmor Hymowitz. Previously, Dr. Hymowitz spent ... |
25.11.2021 | TCG Announces the Addition of TCG iPartners | TCG’s iPartners represents a new ideation advisory group comprised of leading academic investigators... |
29.01.2021 | Dr. Eric Olson joins The Column Group as Science Partner | The Column Group announced the recruitment of Dr. Eric Olson to the firm’s renowned group of Science... |
- | Dr. Helen Hobbs joins The Column Group as Science Partner | The Column Group announced the recruitment of Dr. Helen Hobbs to the firm’s renowned group of Scienc... |
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Mentions in press and media 8
Date | Title | Description | Source |
03.04.2024 | From generative chemistry to computational astrophysics, sta... | Here are a few startups in the cancer space that made headlines recently The recent revelation of Pr... | vator.tv/n... |
17.08.2022 | The Column Group Raises $1.23 Billion in Two New Funds | We are very excited to announce that we have closed the two newest funds of the TCG fund family – Th... | thecolumng... |
10.11.2017 | Exonics Therapeutics Secures $40M in Series A Financing | Exonics Therapeutics, Inc., a Cambridge, Mass.-based biotechnology company, secured $40m in Series A... | finsmes.co... |
15.02.2017 | Surrozen Raises $33M in Series A Financing | Surrozen, Inc., a South San Francisco, CA-based biopharmaceutical company focused on discovering and... | finsmes.co... |
24.12.2014 | Stem cells to transplant in the brain: Stealth UCSF spinout ... | Also listed is Leo Guthart, a managing partner at New York private equity firm TopSpin Partner, and ... | medcitynew... |
20.10.2014 | Daily funding roundup - October 20, 2015 | Yidao Yongche bagged $700M; Gritstone Oncology raised $102M; Zignal Labs landed $15M Zignal Labs, a ... | vator.tv/n... |
- | The Column Group Raises a $725 Million Fourth Fund | The Column Group (TCG), a biotech venture capital firm focused on building innovative drug discovery... | thecolumng... |
- | Stem cells to transplant in the brain: Stealth UCSF spinout ... | A UCSF spinout is growing neuronal stem cells to transplant into the brain, for potential use in tre... | medcitynew... |