MetasTx is creating treatments that prevent and treat prostate cancer metastasis without affecting the Androgen System. An estimated 608,570 Americans died from cancer in 2021. The five-year survival rate of metastatic cancers, those that travel from the primary site to a distant site (also known as Stage 4 or 5), is approximately 30%. This area of research is ripe for advances. Unfortunately, current drug discovery in metastatic cancer has not resulted in therapies with significant increases in patient survival, specificity in drug delivery, or mitigation of deleterious side effects. MetasTx successfully concluded studies revealing the integral role of PAK1 in the regulation of epithelial-to-mesenchymal transition (EMT), a process necessary for early cancer cells to switch to metastatic ones. The stability and efficacy of MTX-101 are significantly superior in inhibiting prostate tumor growth and metastasis in various mouse models of prostate cancer and demonstrate broad applicability across solid tumor cancers.
Location: United States, New Jersey, Bernards Township
Employees: 1-10
Founded date: 2021